Mesenchymal Stem Cells and their prospective
Mesenchymal Stem Cells (MSCs) are adult stem cells that are normally found in the bone marrow. In current works of many cell therapy centers, MSCs has flaunted great potential in numerous regenerative medicines targeted at traditionally “incurable” conditions such as osteoarthritis, aging, hair loss, kidney failure, bone replacement, chronic liver disease, ischemic heart disease, stroke, ligament and tendon injuries.
Referenceshttp://www.knee-surgeon.net.au/stem-cell-therapy/
DIFFERENCES BETWEEN MESENCHYMAL STEM CELLS FROM WARTON JELLY VERSUS ADIPOSE DERIVED STEM CELLS
| Wharton's Jelly MSC | Adipose Derived MSC | |
|---|---|---|
| Source | Umbilical Cord | Adipose tissue under skin |
| Harvest Process | Harvested through enzymatic digestion of the outer layer of umbilical cord | Harvest through operation |
| Chances of disease transmission | Lowest | Lowest |
| Stem cell culture proliferation | High | High |
| Risk of transplant (Graft vs Host disease) | Lower | Lower |
| Side effects to donor | Non-invasion (Not harmful to mother or child) | Invasive (skin is penetrated to reach adipose tissue) |
| Difficulty of collection | No risk or pain imposed | Causes nausea |
| Cell proliferation | Fast | Fast |
ADIPOSE DERIVED MSC
What is Adipose-derived Mesenchymal Stem Cells?
Adipose tissue is the scientific term for fat with the main function of providing our body with energy. It also insulates and cushions our body. But what is more intriguing about these tissues is that it has been discovered that they are also rich in Mesenchymal Stem Cell (MSCs). So “Fats” are, after all, much more useful that what was previously believed!
Referenceshttp://study.com/academy/lesson/adipose-tissue-function-location-definition.html
Why Adipose-Derived MSC?
Adipose-derived MSC provide a promising future in the field of tissue engineering and regenerative medicine, due to their wide availability and multi-potent properties to differentiate into other tissues including bone, cartilage, and muscle. Adipose stem cells have been utilized in studies of osteoarthritis, diabetes mellitus, heart disease, and soft tissue regeneration and reconstruction after mastectomy and facial repair.
Adipose-derived MSCs are easier to harvest than bone marrow and can be obtained in much larger quantities. There is a much shorter time from extraction to the administration of treatment. No culturing or manipulation is needed using this procedure, as opposed to a bone marrow extraction which requires days or weeks to reach the necessary therapeutic threshold.
How do we store Adipose-derived Mesenchymal Stem Cells?
The adipose tissue beneath the abdominal skin can be removed by liposuction or surgery. Once removed, the tissue is transported to our laboratory for processing by our professional laboratory technicians using proprietary know-hows. Once the mesenchymal stem cells are successfully extracted from the tissue, they will be stored in our facility. These stem cells could then be wrought for our clients’ immediate needs, or it could be cryo-preserved for future needs.
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